Squamous cell carcinoma of the tongue in Sprague-Dawley rats using 4-nitroquinoline 1-oxide model
نویسندگان
چکیده
منابع مشابه
the protective effect of the methanolic extract of ferula persica in rat tongue neoplasm (oral squamous cell carcinoma) induced by 4-nitroquinoline-1-oxide (4-nqo)
background cancer is one of the most significant causes of death around the world, and oral squamous cell carcinoma (oscc) represents 90% of oral malignancies. ferula persica has been used for treatment of different diseases in iranian traditional medicine. previous studies reveal some evidence relating to the value of preventing malignancies through f. persica. objectives the aim of the presen...
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Esophageal squamous cell carcinomas (ESCCs) are very common, aggressive tumors, and are often associated with alcohol and tobacco abuse. Because ESCCs exhibit high recurrence rates and are diagnosed at late stages, identification of prognostic and drug targets for prevention and treatment is critical. We used the 4-nitroquinoline-1-oxide (4-NQO) murine model of oral carcinogenesis and the Meado...
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Transgenic rats carrying human c-Ha-ras proto-oncogene (Hras128 rats) have been shown to be highly susceptible to induction of tumors. We have found an early induction of tongue tumors in Hras128 rats treated with 4-nitroquinoline 1-oxide (4NQO). 4NQO was administered to the Hras128 and wild-type Sprague-Dawley (SD) rats for 4 and 8 weeks, respectively. The experiment was terminated at 14 (Hras...
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ژورنال
عنوان ژورنال: Padjadjaran Journal of Dentistry
سال: 2016
ISSN: 2549-6212,1979-0201
DOI: 10.24198/pjd.vol28no1.13510